Just a moment, the page is loading...
Browse ALL STUDIES
Keyword Search
View All Selected
Clear All
Login / Create Account
Login
Create Account
Home
About Us
Privacy Policy
Minimum System Requirements
How To Join
Mission
Data Sponsors
Researchers
How It Works
How to Request Data
Review of Requests
Data Sharing Agreement
Access to Data
Independent Review Panel
Metrics
FAQs
News
Help/Contact Us
Efficacy of Crohn's Disease Treatment Stratified by Disease Phenotype
Proposal
5652
Title of Proposed Research
Efficacy of Crohn's Disease Treatment Stratified by Disease Phenotype
Lead Researcher
Vivek Rudrapatna
Affiliation
University of California - San Francisco
Funding Source
Potential Conflicts of Interest
Data Sharing Agreement Date
10 Jan 2019
Lay Summary
Crohn's Disease is a heterogenous disorder encompassing multiple clinical phenotypes which arise from different biological pathways. Clinical studies and experience suggest that the efficacy of different agents varies by phenotype including anatomical location, disease behavior, and history of prior medication failure. Although this data is commonly collected in clinical trials, it has not been uniformly analyzed or published. As such, clinicians select between treatments based on best guess of efficacy rather than high-quality evidence. Therefore, we propose to re-analyze this existing clinical trial data as an important step towards enabling precision medicine for Crohn's Disease.
Study Data Provided
[{ "PostingID": 2360, "Title": "UCB-C87031", "Description": "A Study to Test the Effect of CDP870 in the Treatment of Crohn's Disease Over 26 Weeks, Comparing CDP870 to a Dummy Drug (Placebo)" },{ "PostingID": 2361, "Title": "UCB-C87032", "Description": "Study to Test the Effect of CDP870 in the Treatment of Crohn's Disease Over 26 Weeks, Comparing CDP870 to a Dummy Drug (Placebo), Following 3 Doses of Active Drug (CDP870)." },{ "PostingID": 3918, "Title": "UCB-C87085", "Description": "Study to Evaluate Efficacy and Safety of Certolizumab Pegol for Induction of Remission in Patients With Crohn's Disease" },{ "PostingID": 3919, "Title": "UCB-CDP870037", "Description": "Clinical Study of CDP870/Certolizumab Pegol in Patients With Active Crohn's Disease" }]
Statistical Analysis Plan
Publication Citation
© 2024 ideaPoint. All Rights Reserved.
Powered by ideaPoint.
Help
Privacy Policy
Cookie Policy
Help and Resources