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The impact of biological interventions on health-related quality of life in adults with Crohn's disease
Proposal
5936
Title of Proposed Research
The impact of biological interventions on health-related quality of life in adults with Crohn's disease
Lead Researcher
Mirjana Stanic Benic
Affiliation
UHC rijeka, krešimirova 42, 51000 Rijeka, Croatia
Funding Source
Potential Conflicts of Interest
Data Sharing Agreement Date
24 June 2019
Lay Summary
Crohn disease is a very aggressive inflammatory gastrointestinal disease which substantially decrease health-related quality of life in patients. Different strategies are involved to influence on disease course (surgery, drug treatment). Biologic drugs represent a revolution in this field of medicine decreasing disease symptoms. The aim of this study is to examine if biologicals could influence on health-related quality of life which represent a final goal for the patients.
Study Data Provided
[{ "PostingID": 2348, "Title": "TAKEDA-C13007", "Description": "A Phase 3, Randomized, Placebo-Controlled, Blinded, Multicenter Study of the Induction and Maintenance of Clinical Response and Remission by Vedolizumab (MLN0002) in Patients With Moderate to Severe Crohn's Disease" },{ "PostingID": 2349, "Title": "TAKEDA-C13011", "Description": "A Phase 3, Randomized, Placebo-Controlled, Blinded, Multicenter Study of the Induction of Clinical Response and Remission by Vedolizumab in Patients With Moderate to Severe Crohn's Disease" },{ "PostingID": 2360, "Title": "UCB-C87031", "Description": "A Study to Test the Effect of CDP870 in the Treatment of Crohn's Disease Over 26 Weeks, Comparing CDP870 to a Dummy Drug (Placebo)" },{ "PostingID": 2361, "Title": "UCB-C87032", "Description": "Study to Test the Effect of CDP870 in the Treatment of Crohn's Disease Over 26 Weeks, Comparing CDP870 to a Dummy Drug (Placebo), Following 3 Doses of Active Drug (CDP870)." },{ "PostingID": 3918, "Title": "UCB-C87085", "Description": "Study to Evaluate Efficacy and Safety of Certolizumab Pegol for Induction of Remission in Patients With Crohn's Disease" },{ "PostingID": 19757, "Title": "UCB-C87059", "Description": "A Phase IIIb Multicenter, Double-blind, Placebo-controlled,Randomized Trial to Examine the Corticosteroid-sparing Effect of Certolizumab Pegol in Patients With Moderate to Severe Crohn's Disease." }]
Statistical Analysis Plan
Publication Citation
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