High-risk human papillomavirus genotyping concordance between paired cervical exfoliated cells and biopsies

High-risk human papillomavirus genotyping concordance between paired cervical exfoliated cells and biopsies

As preventive human papillomavirus (HPV) vaccination coverage continues to increase worldwide, it is crucial to accurately determine the specific types of HPV present in cervical abnormalities. This information is important for monitoring any shifts in the most common HPV types following vaccination. However, obtaining tissue specimens for testing can be challenging. As an alternative, cellular specimens, which are easily collected, are often used for HPV DNA testing in medical settings.Currently, there is a lack of comprehensive studies comparing the accuracy of HPV type determination between cellular and tissue specimens. This research aims to fill that gap by examining the agreement between these two sample types for different grades of cervical abnormalities. The findings from this study will provide valuable insights into the reliability of using cellular specimens in HPV type determination and the potential impact of the severity of the cervical abnormality on test results.

[{ "PostingID": 2794, "Title": "GSK-107638", "Description": "Efficacy, immunogenicity and safety of GlaxoSmithKline Biologicals’ HPV GSK 580299 vaccine in healthy Chinese female subjects" }]